VRAYLAR metabolics, prolactin, and weight change in bipolar I depression studies

Shifts from baseline to endpoint1,2*

Weight change from baseline to endpoint in pivotal studies (6- and 8-week studies)1†

*Metabolic shift defined as: fasting glucose: normal (<100 mg/dL) to high (≥126 mg/dL), borderline (≥100 mg/dL and <126 mg/dL) to high; total cholesterol: normal/borderline (<240 mg/dL) to high (≥240 mg/dL); fasting triglycerides: normal/borderline (<200 mg/dL) to high (≥200 mg/dL).1,2

Recommended dose range of VRAYLAR is 1.5–3 mg/day for depressive episodes.1